Lacto-N-neotetraose (LNnT) is a key component of the human milk oligosaccharide (HMO) family, renowned for its pivotal role in infant health and development. As one of the most abundant neutral core HMOs in human breast milk, LNnT contributes to establishing a healthy gut microbiota and modulating the immune system from the earliest stages of life.
| Item | Lacto-N-neotetraose (LNnT) |
|---|---|
| Catalog number | DS13007324 |
| CAS number | 13007-32-4 |
| Glycan structure | Galβ1-4GlcNAcβ1-3Galβ1-4Glc |
| Molecular formula | C26H45N1O21 |
| Molecular weight | 707.63 g/mol |
LNnT plays a fundamental role in shaping the early gut microbiome by selectively nourishing Bifidobacteria, among the first microbial colonizers in the human intestine. These beneficial bacteria enhance microbiome diversity, support digestion, and serve as a natural barrier against pathogens.
Human milk oligosaccharides like LNnT act as immune educators, supporting the development and function of the infant immune system. LNnT has been associated with enhanced wound healing, reduced inflammation, and the induction of type 2 immune responses, including the activation of T helper and B cells.
An imbalance in the gut microbiota—known as dysbiosis—can lead to discomfort and various digestive challenges. Studies have shown that when combined with other HMOs such as 2'-fucosyllactose (2'FL), LNnT contributes to symptom relief and improved quality of life in individuals with irritable bowel syndrome (IBS).
Alfa Chemistry offers a reliable and scalable supply of HMOs tailored for the dietary supplements and functional nutrition industry. Our LNnT is manufactured under stringent quality controls, ensuring product integrity, batch consistency, and regulatory compliance. Whether you're developing infant formula, synbiotics, or advanced gut health supplements, we deliver solutions backed by scientific precision and supply chain reliability.
Our products and services are for research use only and cannot be used for any clinical purposes.