Lacto-N-tetraose (LNT)
Lacto-N-tetraose (LNT)
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Lacto-N-tetraose (LNT)

Lacto-N-tetraose (LNT) is one of the most abundant and structurally foundational neutral human milk oligosaccharides (HMOs). Naturally present in breast milk, LNT plays a pivotal role in shaping the infant gut microbiome and supporting immune development. This tetrasaccharide is composed of D-galactose, N-acetyl-D-glucosamine, and D-glucose units, forming a Galβ1-3GlcNAcβ1-3Galβ1-4Glc structure.

As a non-fucosylated, non-sialylated HMO with a type 1 core, LNT is an essential building block in HMO research and formulation. Alfa Chemistry now offers this high-purity compound for use in dietary supplement development, infant formula enhancement, and gut health studies.

Product Highlights

  • Naturally inspired HMO identical to that found in human breast milk
  • Supports bifidogenic growth, especially Bifidobacterium longum and Bifidobacterium breve
  • Non-fucosylated, non-sialylated neutral oligosaccharide
  • High purity and consistent quality suitable for nutraceutical and functional food applications
  • Regioisomer of LNnT, offering alternative glycan structures for diversified HMO formulations

Specifications

ItemLacto-N-tetraose (LNT)
Catalog numberDS14116688
CAS number14116-68-8
Glycan structureGalβ1-3GlcNAcβ1-3Galβ1-4Glc
Molecular formulaC26H45NO21
Molecular weight707.63 g/mol

Nutritional & Health Benefits

  • Promotes Beneficial Gut Flora

LNT selectively supports the growth of beneficial bifidobacteria, helping establish a balanced gut microbiota in newborns and infants.

  • Immune Modulation

Emerging studies suggest that LNT may contribute to immune system development by modulating immune responses and enhancing barrier function.

  • Anti-Adhesive Pathogen Defense

By mimicking epithelial cell receptors, LNT interferes with the adhesion of pathogenic bacteria, reducing their ability to colonize the gut lining.

  • Microbial Fermentation Support

Acts as a fermentable substrate for gut microbes, aiding in short-chain fatty acid production and overall gut health.

  • Potential Biomarker Relevance

Elevated LNT levels have been observed in the breast milk of mothers with rotavirus-positive infants, correlating with microbial community shifts in both maternal milk and infant stool.

Why Choose Alfa Chemistry?

Alfa Chemistry offers a reliable and scalable supply of HMOs tailored for the dietary supplements and functional nutrition industry. Our LNT is manufactured under stringent quality controls, ensuring product integrity, batch consistency, and regulatory compliance. Whether you're developing infant formula, synbiotics, or advanced gut health supplements, we deliver solutions backed by scientific precision and supply chain reliability.

Our products and services are for research use only and cannot be used for any clinical purposes.

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