What is Dihydromyricetin (DHM) and what are its primary sources?
Dihydromyricetin (DHM) is a flavonoid compound primarily found in the Japanese raisin tree (Hovenia dulcis) and other plants like the Ampelopsis grossedentata. It has been traditionally used in Chinese herbal medicine and is noted for its potential health benefits, including liver protection and reducing the effects of alcohol consumption.
How does DHM contribute to liver protection according to recent studies?
Recent studies, such as those conducted by the University of Southern California, suggest that DHM can help protect the liver from damage. It appears to do this by promoting the activity of certain enzymes that metabolize alcohol, helping to reduce the liver's workload and minimize damage often associated with excessive alcohol consumption.
What are the potential mechanisms of action for DHM in reducing hangover symptoms?
DHM may alleviate hangover symptoms by enhancing the breakdown of acetaldehyde, a toxic byproduct of alcohol metabolism, thereby reducing its duration and harmful effects in the body. It can also modulate GABA receptors in the brain, potentially reducing alcohol-related anxiety and sedation.
How does DHM affect alcohol metabolism in the human body, and what are the implications for alcohol tolerance?
DHM affects alcohol metabolism mainly by increasing the efficiency of enzymes such as alcohol dehydrogenase and acetaldehyde dehydrogenase, which speed up the conversion of alcohol to less harmful substances. This action can potentially increase alcohol tolerance, leading to reduced sensations of intoxication and faster recovery from alcohol consumption.
Are there any side effects or risks associated with the use of DHM?
While DHM is generally considered safe, especially in traditional medicine practices, potential side effects or risks have not been extensively studied. Some users may experience mild symptoms such as nausea or gastrointestinal discomfort. As with any supplement, it is advised to consult a healthcare provider before use, particularly for individuals with underlying health conditions or those taking other medications.
