CAS 22880-03-1
Catalog DS22880031
Molecular Formula C18H32O2
Molecular Weight 280.44
Appearance White powder
Content 40.0%
Storage Store in a cool, dry, ventilated place, sealed away from light.
Package 1 kg/bag, 25 kg/drum
Shelf life 24 months
Dietary Supplements
Health Food Industry
Food Ingredients
Conjugated linoleic acid (CLA) is a collective term for a series of isomers of linoleic acid with conjugated double bonds. The conjugated double bonds are usually at positions 9 and 11 or 10 and 12. According to the conformation of the double bond, CLA can be cis-fats or trans-fats. There are 28 forms of CLA based on different structures. CLA exists mostly in meat and dairy products, and is neither poisonous nor has any side effects. It has beneficial effects on anti-tumor, preventing arteriosclerosis, inhibiting fat deposition, modulating immune function, etc. Therefore, CLA can be added to food to improve food nutrition, which is beneficial to human health. CLA is also sold as a dietary supplement based on its health benefits and is generally safe when taken as prescribed.
Food Sources
Good food sources of CLA are mainly meat and dairy products, but also in small amounts in some non-animal products, such as Agaricus bisporus and Agaricus subrufescens. CLA can be found in abundance in some animal products from ruminants such as lamb and beef. It is worth noting that CLA content is higher in grass-fed animal products than in grain-fed products. Grass-based diets or feeding animals plant sources of linoleic acid, such as sunflower, soybean, or flaxseed oil, can both increase animal products' CLA content. In addition, CLA from ruminant digestion accumulates in dairy products, including cheese, butter, and yogurt.
Benefits of CLA
CLA has a variety of physiological roles and is therefore used in CLA supplements to provide health benefits. But many studies have involved animals rather than humans, so further evidence is needed to definitively confirm the benefits of supplementation with CLA for humans. The following sections describe the possible health benefits of CLA.
In many studies on mice, rats and other experimental animals and on human tumor cells, it has been observed that CLA has a broad-spectrum anti-cancer effect. It can inhibit the occurrence of mammary gland tumors in mice, and also shows an obvious inhibitory effect on the expansion of breast cancer MCA-7 cells, lung cancer A-427 cells, and rectal cancer HT-29 cells cultured in vitro [1].
Antitumor effect
When plaque builds up in the arteries, atherosclerosis occurs, a risk factor for heart disease. As early as 1994, it was reported that CLA could reduce the concentration of total cholesterol and low-density lipoprotein cholesterol in rabbit plasma, change the ratio of high and low-density lipoprotein cholesterol, and inhibit the occurrence of atherosclerosis.
Prevent arteriosclerosis
Reference
- Erickson, K. L.; et al. Factors affecting the production of conjugated linoleic acid in dairy cows mechanisms of reduced metastasis by conjugated linoleic acid research and reviews. Dairy. 2001.
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