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- Folic Acid, food grade
Catalog | DS59303 |
CAS | 59-30-3 |
Structure | ![]() |
Synonyms | Pteroylglutamic Acid; Folate; Vitamin M; Folacin; PteGlu |
IUPAC Name | (2S)-2-[[4-[(2-amino-4-oxo-3H-pteridin-6-yl)methylamino]benzoyl]amino]pentanedioic acid |
Molecular Weight | 441.4 |
Molecular Formula | C19H19N7O6 |
InChI | InChI=1S/C19H19N7O6/c20-19-25-15-14(17(30)26-19)23-11(8-22-15)7-21-10-3-1-9(2-4-10)16(29)24-12(18(31)32)5-6-13(27)28/h1-4,8,12,21H,5-7H2,(H,24,29)(H,27,28)(H,31,32)(H3,20,22,25,26,30)/t12-/m0/s1 |
InChI Key | OVBPIULPVIDEAO-LBPRGKRZSA-N |
Melting Point | 250 °C |
Purity | 99%+ |
Appearance | Ginger yellow powder |
Shelf Life | 24 months |
Storage | Store in a cool and dry place, away from light. |
Certification | KOSHER/GMP/MUL/HALAL/ |
EC Number | 200-419-0 |
Isomeric SMILES | C1=CC(=CC=C1C(=O)N[C@@H](CCC(=O)O)C(=O)O)NCC2=CN=C3C(=N2)C(=O)NC(=N3)N |
Packaging | 10/20/25/50 kg |
Standard | FCC, USP, EP |
Type | Vitamin B9 |
What is folic acid and why is it important in nutrition?
Folic acid is a synthetic form of folate, a type of B vitamin (B9), which plays a crucial role in DNA synthesis, repair, and methylation, as well as in the formation of red blood cells. It is particularly important during periods of rapid growth, such as during pregnancy and fetal development, as it helps prevent neural tube defects in the developing fetus.
What are the primary food sources of folic acid and how does it differ from natural folate in food?
Folic acid is typically found in fortified foods and supplements, whereas naturally occurring folate is present in food sources like leafy green vegetables, citrus fruits, beans, and whole grains. While both forms contribute to dietary folate equivalents, folic acid is more efficiently absorbed by the body compared to natural folate.
How much folic acid is recommended for different populations, and why might these requirements vary?
The recommended daily intake of folic acid varies depending on age, sex, and life stage. For adults, the RDA is approximately 400 micrograms, but it increases to 600 micrograms for pregnant women to support fetal development. The requirements may vary due to factors such as nutritional needs during pregnancy, individual health conditions, and differences in metabolism.
What are the potential health benefits associated with adequate folic acid intake?
Adequate folic acid intake is associated with reduced risks of certain birth defects, cardiovascular diseases, and certain types of cancer. It may also support brain health and contribute to the reduction of homocysteine levels, which are linked to heart disease.
Are there any risks associated with excessive folic acid consumption, and what is the upper limit for daily intake?
Excessive folic acid intake, typically from supplements or fortified foods, can mask vitamin B12 deficiency symptoms and potentially exacerbate neurological problems. The established upper intake level for adults is 1,000 micrograms per day of folic acid from fortified foods and supplements to avoid these potential adverse effects.
How is food-grade folic acid produced and utilized in fortified food products?
Food-grade folic acid is synthesized and added to fortified food products such as cereals, flour, and certain beverages to help populations achieve adequate intake levels. This fortification strategy is used to reduce the incidence of folate deficiency and associated health risks within the general population.
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