Catalog | DS66575299 |
CAS | 66575-29-9 |
Structure | ![]() |
Description | Coleus forskohlii |
Molecular Weight | 410.50 |
Appearance | White powder |
Shelf Life | 24 months |
Storage | Store in a dry, airtight container under an inert atmosphere, away from light. |
Chemical Family | Terpenes |
EC Number | 266-410-9 |
Harmonized Tariff Code | Sch B# 3822.00.0002 (CN,CH,AU:HTS# 3822.00.60.00) |
RTECS Number | QL6150000 |
Signal Word | WARNING |
What is forskolin and where is it derived from?
Forskolin is a chemical compound found in the root of the plant Plectranthus barbatus (also known as Coleus forskohlii), which belongs to the mint family. This herb is native to India and has been traditionally used in Ayurvedic medicine.
What are the traditional uses of forskolin in herbal medicine?
Traditionally, forskolin has been used in herbal medicine to treat a variety of conditions, including heart disorders, respiratory issues, and digestive problems. It has been valued for its supposed ability to improve circulation, support heart health, and promote weight loss.
How does forskolin purportedly aid in weight loss?
Forskolin is believed to aid in weight loss by exerting its effects on enzymes that are involved in the breakdown of fat cells. It is thought to stimulate the production of cyclic AMP (cAMP), an important molecule in fat and glucose metabolism, which in turn may enhance the process of lipid breakdown.
What are the claims regarding forskolin's role in supporting cardiovascular health?
Some proponents suggest that forskolin can support cardiovascular health by helping to dilate blood vessels, leading to an improvement in blood flow and a potential reduction in blood pressure. This vasodilatory effect is attributed to its ability to increase levels of cAMP.
Are there any notable risks or side effects associated with forskolin supplementation?
Yes, forskolin can pose several risks and side effects, especially at high doses or with prolonged use. These may include low blood pressure, rapid or irregular heart rate, headache, dizziness, and increased risk of bleeding. It can also interact with other medications, such as blood thinners, and should be used with caution in individuals with cardiovascular conditions or those taking other medications.
What does current scientific research say about the efficacy of forskolin for weight management and other health benefits?
Current scientific evidence on forskolin's efficacy for weight management and other health benefits is limited and inconclusive. Some studies suggest potential benefits, but many of these are small in scale or not adequately controlled. More rigorous clinical trials are needed to confirm these effects and to better understand the safety profile of forskolin.
How should individuals approach the use of forskolin if considering it for health purposes?
Individuals should approach the use of forskolin with caution. It is essential to consult with a healthcare provider before starting any new supplement, especially for those with preexisting health conditions or those who are pregnant or breastfeeding. This ensures that any potential interactions or side effects can be properly managed.
Our products and services are for research use only and cannot be used for any clinical purposes.