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- Nicotinamide, food grade
Catalog | DS98920 |
CAS | 98-92-0 |
Synonyms | 3-Pyridinecarboxamide; Nicotinic Acid Amide; Pyridine-3-Carboxamide; Vitamin PP |
IUPAC Name | Pyridine-3-carboxamide |
Molecular Weight | 122.12 |
Molecular Formula | C6H6N2O |
InChI | InChI=1S/C6H6N2O/c7-6(9)5-2-1-3-8-4-5/h1-4H,(H2,7,9) |
InChI Key | DFPAKSUCGFBDDF-UHFFFAOYSA-N |
Melting Point | 128-131 °C |
Purity | 99%+ |
Appearance | White powder |
Shelf Life | 24 months |
Storage | Store in a cool and dry place, away from light |
Certification | KOSHER/GMP/MUL/HALAL/ |
EC Number | 202-713-4 |
Isomeric SMILES | C1=CC(=CN=C1)C(=O)N |
Packaging | 20 kg |
Type | Vitamin B3 |
What is nicotinamide, and how is it different from niacin?
Nicotinamide, also known as niacinamide, is a form of vitamin B3. It is derived from niacin and is one of the two major forms of vitamin B3. Unlike niacin, nicotinamide does not cause flushing and is often used in dietary supplements and fortified foods.
What are the primary health benefits associated with nicotinamide intake?
Nicotinamide plays a crucial role in the body by converting food into energy, supporting cellular repair, and maintaining healthy skin. It is involved in DNA repair and the synthesis of NAD+ (nicotinamide adenine dinucleotide), a coenzyme essential for cellular metabolism.
How does food-grade nicotinamide contribute to skin health?
Food-grade nicotinamide is used in many dermatological products due to its anti-inflammatory properties, which can reduce acne and hyperpigmentation. It also helps in reducing the appearance of fine lines and boosting the skin's barrier function.
What dietary sources are rich in nicotinamide?
Nicotinamide can be found in many foods, including meat, fish, nuts, seeds, and green vegetables. Fortified foods and dietary supplements can also provide nicotinamide to ensure adequate intake.
Can nicotinamide supplementation support cognitive health or aging?
Research suggests that nicotinamide may support cognitive health by improving mitochondrial function and cellular energy production. By enhancing NAD+ levels, it might also contribute to healthy aging, although more studies are needed to confirm these effects.
Are there any notable side effects or risks associated with nicotinamide consumption?
Nicotinamide is generally considered safe with low toxicity levels. However, excessive intake can lead to adverse effects such as liver damage, gastrointestinal issues, or increase in blood sugar levels. It's important to follow recommended dietary guidelines.
How is food-grade nicotinamide used in nutritional supplements?
Food-grade nicotinamide is often used in multivitamin and mineral supplements to support overall health. It ensures the required intake of vitamin B3 without the flushing effects associated with niacin.
In what ways might nicotinamide be beneficial for metabolic health?
Nicotinamide plays a role in glucose metabolism and insulin sensitivity. Some evidence suggests that sufficient levels may help regulate blood sugar levels and reduce the risk of type 2 diabetes, though further research is needed.
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